Connect with us


Rutgers Scientists Develop Promising Oral COVID-19 Treatment

Avatar of Arsi Mughal



Rutgers Scientists Develop Promising Oral COVID-19 Treatment

(CTN News) – Rutgers University researchers have significantly advanced in developing a novel oral treatment for COVID-19, which could provide an alternative to Pfizer’s Paxlovid, particularly for high-risk patients. Animal studies have proven that their innovative research slows the progression of the disease with a viral papain-like protease inhibitor.

Treating the gaps in current treatment

Professor Jun Wang, an associate professor at Rutgers’ Ernest Mario School of Pharmacy, highlighted the urgent need for additional and diverse treatment options. Although vaccines have been rolled out, COVID-19 remains one of the leading causes of death in the United States. As a result, he highlighted the crucial role that new treatments can play in preparing for future viral mutations that may compromise the efficacy of existing drugs such as Paxlovid in the future.

oral medicine 970 x 440

Targeting the virus’s life cycle

A protein called PLpro is key to the virus’s life cycle, and it’s present in all known strains of COVID-19. Wang’s team designed and synthesized 85 drug candidates based on structural information provided by Rutgers’ Arnold Lab at the Center for Advanced Biotechnology and Medicine.

SEE ALSO: Global COVID-19 Cases Surge by 52% in Recent Weeks, WHO

The Jun12682: A Game-Changer

Known as Jun12682, it inhibited multiple strains of SARS-CoV-2, including those resistant to Paxlovid. Trials on mice infected with SARS-CoV-2 showed Jun12682 reduced viral lung loads and pulmonary lesions and improved survival.

Additionally, Jun12682 doesn’t have the same drug interaction issues as Paxlovid, which is important since many high-risk patients take several prescriptions. Rutgers has patented this promising compound and is looking for partners to help it progress.

Researchers have disseminated the study on bioRxiv and submitted it for publication in a scientific journal, marking an important step forward in the fight against COVID-19 and offering hope to high-risk patients everywhere.

Related CTN News:

New Severe Asthma Treatment: Goodbye Inhaled Steroids

Sanofi Ends Lung Cancer ADC Development After Failed Phase III Trial.

Dispelling Common Eyelash Extensions Myths!

Arsi Mughal is a staff writer at CTN News, delivering insightful and engaging content on a wide range of topics. With a knack for clear and concise writing, he crafts articles that resonate with readers. Arsi's pieces are well-researched, informative, and presented in a straightforward manner, making complex subjects accessible to a broad audience. His writing style strikes the perfect balance between professionalism and casual approachability, ensuring an enjoyable reading experience.

Continue Reading

CTN News App

CTN News App

Recent News


compras monedas fc 24

Volunteering at Soi Dog

Find a Job

Jooble jobs

Free ibomma Movies