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“Risk of Early-Onset Dementia is Increased By Alcohol Misuse And Loneliness.”



"Risk of Early-Onset Dementia is Increased By Alcohol Misuse And Loneliness."

(CTN News) – Pioneering research has discovered that early-onset dementia is significantly heightened by alcohol misuse, lower socioeconomic background, feelings of loneliness, and hearing impairment.

This is the first study to suggest that lifestyle changes can reduce the risk of early-onset dementia, similar to preventing in older individuals.

The study analyzed data from 350,000 individuals under 65 and identified 15 factors that increase the risk of early-onset dementia, including education level, socioeconomic status, health issues, and lifestyle factors. Addressing these factors could help mitigate the risk of developing early-onset dementia.

Further research is needed to understand the underlying mechanisms and develop effective prevention strategies. This study provides valuable insights into preventing and managing early-onset by focusing on lifestyle and health-related factors.

Dementia poses a significant challenge to the healthcare system in the UK, and recent research indicates that the number of people affected by this condition could reach 1.7 million by 2040. Currently, there are approximately 900,000 individuals living in Britain, with over 70,800 of them experiencing early-onset dementia.

Professor Sebastian Köhler, a renowned expert in neuroepidemiology from Maastricht University and one of the lead authors of the study, highlights that previous research on older individuals has identified several modifiable risk factors.

These factors include not only physical aspects but also mental health considerations such as avoiding chronic stress, loneliness, and depression.

The surprising revelation that these risk factors also apply to young-onset dementia opens up possibilities for risk reduction in this particular group.

Dr. Janice Ranson, a senior research fellow at the University of Exeter, emphasizes that this research represents a breakthrough in identifying the potential for reducing the risk of young-onset dementia.

She believes that it could mark the beginning of a new era in interventions aimed at preventing new cases of this condition.

Dr. Leah Mursaleen, the head of clinical research at Alzheimer’s Research UK, which co-funded the study, describes the evolving understanding of risk and the potential for individual and societal risk reduction.

In recent years, there has been a growing consensus regarding 12 specific modifiable risk factors associated with dementia, such as smoking, blood pressure, and hearing loss. It is now acknowledged that up to 40% of dementia cases worldwide can be linked to these factors.

This groundbreaking study sheds light on the factors that influence the risk of young onset, filling an important gap in our knowledge. Further research is crucial to build upon these findings in more comprehensive studies.

The study has been published in JAMA Neurology, a reputable medical journal.


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