Connect with us

How COVID-19 Can Cause Long-Term Pain Found

Published

on

Delta 8 Disposable Vape Pen

The researchers have found important insights into how the virus that causes COVID-19, SARS-CoV-2, can cause long-term pain, which could lead to a potential treatment.

Experiments were conducted using a hamster model of intranasal COVID-19 infection, which closely mimics the symptoms experienced by people.

A significant number of people with long COVID-19 experience sensory abnormalities, including pain, according to Randal Serafini, a Ph.D. student at the Icahn School of Medicine at Mount Sinai.

SARS-CoV-2 triggers biochemical changes in the dorsal root ganglia, a pain-transmitting structure, Serafini said.

The researchers found that the SARS-CoV-2 infection left a gene expression signature in the dorsal root ganglia that remained even after the virus cleared.

The signature matched gene expression patterns seen in other types of pain, they said.

A Society for Pharmacology and Experimental Therapeutics annual meeting was held between April 2-and 5 in Philadelphia, US.

According to Serafini, “our findings may lead to new therapies for patients suffering from acute and chronic COVID-19.”

COVID-19 Causes Long-Term Pain, Scientists said

SARS-CoV-2 has long-term effects on the body in dramatically new ways, further demonstrating why people should not become infected,” the scientist said.

As infection progressed, SARS-CoV-2-infected hamsters developed a slight hypersensitivity to touch that became stronger after 30 days.

They then tested whether other RNA viruses promote similar responses to the Influenza A virus.

As opposed to SARS-CoV-2, Influenza A caused an early hypersensitivity more severe but faded after four days, according to researchers.

SARS-CoV-2 caused more profound changes in gene expression levels of neuron-specific signaling genes in the dorsal root ganglia than influenza, the researchers found.

Flu-infected hamsters showed no signs of long-term hypersensitivity after recovery from viral infection while SARS-CoV-2-infected hamsters showed worsened hypersensitivity.

Related CTN News:

Covid-19 Fourth Wave In China, Hong Kong Raises Alarm For India
Omicron BA 2 Rises In The U.S., But Experts Remain Optimistic
Will Omicron BA.2 Cause Another Wave Of Infection In The US?
Continue Reading

CTN News App

CTN News App

Recent News

BUY FC 24 COINS

compras monedas fc 24

Volunteering at Soi Dog

Find a Job

Jooble jobs