5 Mins to Tell You Why the HPV Genotyping Test is Important

HPV Genotyping Test: Human Papillomavirus (HPV) is one of the most common sexually transmitted viruses. There are about 100 types of HPV, which vary in genetic and carcinogenic potential. HPV 16 and 18, in particular, are the most common high-risk HPV worldwide, and nearly 70% of cervical cancers are due to infection by these genotypes.¹

Considering the threat of high-risk HPV and importance of HPV detection, a variety of tests are being conducted, including TCT test, HPV DNA test, cervicography, etc. Sometimes, the lab will specifically report if you have the two highest-risk HPV 16 and HPV 18 based on the HPV genotyping test.

Significance of HPV Genotyping Test

HPV genotyping usually looks for high-risk HPV genotypes that are more likely to lead to cervical cancer, such as HPV 16 and 18. It benefits not only individuals but also collectives.

• Individual benefits

First of all, HPV genotyping test contributes to the risk stratification of HPV-positive women. Genotyping of high-risk HPV could be helpful for the risk stratification of HPV-positive women. Persisting high-risk HPV infections can cause cervical cancer.

But HPV genotyping is excellent at identifying different kinds of HPV genotypes, especially high-risk HPV 16 and HPV 18. This enables HPV-positive women to know the HPV genotype and access immediate and exclusive treatment.

• Collective interests

In addition, the HPV genotyping test also plays an essential role in the regional epidemiological investigation. The distribution and prevalence of HPV types vary by region, which makes the regional epidemiological investigation more challenging.

But with the assistance of the HPV genotyping test, most regions can adopt cervical cancer screening programs and type-specific vaccines based on HPV genotypes to prevent cervical cancer.

Know More about HPV Genotyping with Sansure

As HPV genotyping test has assumed a significant role in preventing cervical cancer, Sansure applies the HPV genotyping to its products. S3108E Human Papillomavirus DNA (23 genotypes) Diagnostic Kit （HPV G23） is here to help better understand the HPV genotyping test.

1. Have wide coverage for 23 HPV genotypes

Sansure’s S3108E HPV G23—Human Papillomavirus DNA (23 genotypes) Diagnostic Kit is an in vitro nucleic acid amplification test, which is capable of detecting 23 high-risk HPV genotypes (type 6, 11, 16, 18, 26, 31, 33, 35, 39, 42, 43, 45, 51, 52, 53, 56, 58, 59, 66, 68, 73, 81, 82) present in exfoliated cells from females’ cervix.

2. Provide test results to identify specific HPV genotypes

The test results gained from this diagnostic kit can be used to identify HPV genotypes. With the PCR technology and Taqman technology, this diagnostic kit uses pairs of specific primers and exclusive fluorescence probes of the 23 HPV-DNA types mentioned above to test the specific DNA fragments of 23 types of HPV-DNA for genotyping by dividing into 6 reaction tubes.

3. Delivers the result faster, with less chance of contamination

Delivering fast results is one of the prominent features of this diagnostic kit. By applying one-tube fast-release technology, Sansure’s Human Papillomavirus DNA (23 genotypes) Diagnostic Kit HPV G23 test can quickly extract the sample DNA/RNA through simple operations, providing the result in 70 minutes. Additionally, it is worth mentioning that this diagnostic kit has an anti-contaminated internal control system to ensure the extracts are not contaminated and thus a reliable result.

Conclusion

Sansure has been committed to developing more affordable and well-used gene technology, products, and services to benefit people worldwide since its establishment in 2008.

For instance, Sansure’s Human Papillomavirus DNA (23 genotypes) Diagnostic Kit （HPV G23） is an innovative product that is excellent for HPV genotyping tests. It applies Sanure’s advanced technology and can efficiently provide test results to identify specific HPV genotypes with less contamination. In the future, Sansure will stick to the path of cervical cancer prevention.

Reference

[1]A review of methods for detect human Papillomavirus infection

Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507852/